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Tile Image

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F_Image18_Malik_96dpi_4003x3006.jpg
F_Image18_Malik_96dpi_4003x3006.jpg
Title: Tile Image
Description: A tile image showing many cells. The darker regions are cell nuclei. Red is actin, green is the protein fibronectin, and white is transforming growth factor beta (TGFB). There is a strong presence of fibronectin.

This image was taken using the Zeisse microscope with a 63x oil objective. The green channel is the fibronectin, white is transforming growth factor beta, and the red is actin. This is a fibronectin stained sample.

The research that I am currently working on is how fibronectin assembly induces epithelial to mesenchymal transition (EMT) in mammary epithelial cells via transforming growth-beta signaling. EMT is involved in the progression of breast cancer. TGFB induces EMT and my research focuses on the role of the extracellular matrix protein fibronectin in EMT. The proposed hypothesis is that increasing fibronectin assembly increases the secretion/expression of TGFB. TGFB binds to the receptors on fibronectin.

Roshni Malik, Student, Biomedical Engineering
This image was taken using the Zeisse microscope with a 63x oil objective. It was taken using Zeisse software.
Identifier: ttlg-18
Citation:
“Tile Image,” VCU Libraries Gallery, accessed May 4, 2024, https://gallery.library.vcu.edu/items/show/2745.